Prescription skincare, examined.Research checked October 7, 2026
THE SKIN
LEDGER

Explore a concern

Pigmentation

Products in a shared category may have different indications and safety requirements. A clinician determines whether a treatment fits your diagnosis.

Pigmentation

CoreAge Rx

Spot On

Published offer
$42–$65/month advertised across the skincare range; product quote required

Compounded topical
Pigmentation02

Musely

The Spot Cream

Published offer
$36/month advertised; two-month supply

Compounded prescription
Pigmentation03

Musely

The Spot Pill

Published offer
$30/month advertised; three-month supply

Compounded prescription
Pigmentation04

Musely

The Spot Peel

Published offer
$99 per treatment advertised

Compounded prescription
Pigmentation05

Musely

The Body Cream

Published offer
$49/month advertised; two-month supply

Compounded prescription
Pigmentation06

Musely

The Private Cream

Published offer
$36/month advertised; two-month supply

Compounded prescription
Pigmentation07

Agency

Dark Spot Rx

Published offer
$110 for 18 g; described as 60-day supply

Compounded topical
Pigmentation08

Likeness Rx

Dark Spot Cream

Published offer
$165 due for three months; renews at $165

Compounded topical
Pigmentation10

Strut Health

Melasma Formula

Published offer
$69 for 15 g; auto-refill advertised

Compounded topical
Pigmentation11

Skin Medicinals

Hyperpigmentation Compound

Published offer
From $48 shown for a 4% option; stronger formulas need their own quote

Compounded topical
Pigmentation12

Nurx

Hydroquinone Cream

Published offer
$90 for a three-month supply; clinical costs additional

Prescription topical
Pigmentation13

Nurx

Dark Spots Formula

Published offer
$90 for a three-month supply; clinical costs additional

Compounded topical
Pigmentation14

Tri-Luma

Triple Combination Cream

Published offer
Individual pharmacy quote; insurance and savings eligibility vary

Manufactured prescription